Which class of anti-hypertensive agents do drug names ending in "-zosin" belong to?

Enhance your understanding of anti-hypertensive agents with our comprehensive test. Utilize detailed flashcards and multiple-choice questions, complete with hints and explanations. Maximize your readiness!

Drug names ending in "-zosin" are recognized as belonging to the class of α1 antagonists. These medications work by selectively blocking alpha-1 adrenergic receptors, which leads to vasodilation and a subsequent decrease in blood pressure. This mechanism is particularly beneficial in managing hypertension, as it reduces the resistance in blood vessels.

The use of α1 antagonists can also aid in alleviating symptoms associated with conditions like benign prostatic hyperplasia, as these agents facilitate the relaxation of smooth muscle in both blood vessels and the urinary tract. This dual action highlights their unique role among anti-hypertensive agents.

In contrast to the other classes mentioned, such as β-blockers, ACE inhibitors, and calcium channel blockers, α1 antagonists have a distinct action focusing on the adrenergic system. Beta-blockers primarily inhibit the effects of adrenaline on the heart, ACE inhibitors block the conversion of angiotensin I to angiotensin II leading to decreased blood volume, and calcium channel blockers prevent calcium from entering cells of the heart and blood vessel walls, thus reducing vascular contractility. Each class has its own mechanism and use in treatment, but "-zosin" specifically identifies α1 antagonists.

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