What is the secondary indication for thiazides?

Thiazide diuretics are primarily used for the management of hypertension; however, they also have a secondary indication in the treatment of heart failure. In this context, thiazides help to reduce volume overload and edema associated with heart failure by promoting diuresis, which decreases the heart's workload and improves symptoms. By lowering blood pressure and reducing fluid retention, thiazides can contribute to better overall management of heart failure patients, making it a valuable secondary indication in their use.

The other options lack the same direct connection to thiazide therapy. While cardiac arrhythmias, stroke prevention, and angina pectoris have their own treatment modalities, thiazides are not primarily employed for these conditions in the same way they are for hypertension and heart failure.