Potassium sparing diuretics are primarily used to address which of the following?

Potassium-sparing diuretics are primarily utilized to prevent hypokalemia, which is a condition characterized by low potassium levels in the blood. These diuretics function by promoting the excretion of sodium and water while simultaneously helping the body retain potassium. This mechanism is particularly important because traditional diuretics can lead to the loss of potassium, potentially causing or exacerbating hypokalemia.

While these diuretics can also be effective in managing fluid retention, high blood pressure, and edema, their distinctive role and primary indication in clinical practice is the preservation of potassium levels. Thus, their main therapeutic purpose is to address hypokalemia, making it the most accurate answer.